{"id":7119,"date":"2023-09-27T17:56:46","date_gmt":"2023-09-27T15:56:46","guid":{"rendered":"https:\/\/mycan.builtbygo.com\/?p=7119"},"modified":"2024-11-15T17:52:30","modified_gmt":"2024-11-15T15:52:30","slug":"co-jsou-kanabinoidy","status":"publish","type":"post","link":"https:\/\/mycannabis.cz\/en\/co-jsou-kanabinoidy\/","title":{"rendered":"What are cannabinoids?"},"content":{"rendered":"

Kanabinoidy, kter\u00e9 se p\u0159irozen\u011b vyskytuj\u00ed v rostlin\u011b konop\u00ed, jsou slou\u010deniny, kter\u00e9 p\u016fsob\u00ed na va\u0161e t\u011blo a vyvol\u00e1vaj\u00ed \u0159adu r\u016fzn\u00fdch potenci\u00e1ln\u00edch \u00fa\u010dink\u016f a v\u00fdhod. V tomto \u010dl\u00e1nku najdete v\u0161echny d\u016fle\u017eit\u00e9 informace, kter\u00e9 v\u00e1m pomohou pochopit v\u00fdznam kanabinoid\u016f v l\u00e9\u010div\u00e9m konop\u00ed a jejich p\u0159\u00ednos pro podporu va\u0161eho zdrav\u00ed a pohody.<\/p>\n

Co jsou kanabinoidy?<\/h2>\n

Kanabinoidy jsou skupinou chemick\u00fdch slou\u010denin, kter\u00e9 se nach\u00e1zej\u00ed v rostlin\u011b konop\u00ed. V t\u011ble lid\u00ed a dal\u0161\u00edch \u017eivo\u010dich\u016f interaguj\u00ed s endokanabinoidn\u00edm syst\u00e9mem, kter\u00fd se pod\u00edl\u00ed na regulaci r\u016fzn\u00fdch fyziologick\u00fdch proces\u016f, v\u010detn\u011b n\u00e1lady, pam\u011bti, vn\u00edm\u00e1n\u00ed bolesti, chuti k j\u00eddlu a imunitn\u00ed reakce.<\/p>\n

Kolik kanabinoid\u016f existuje?<\/h3>\n

Existuj\u00ed t\u0159i hlavn\u00ed typy kanabinoid\u016f:<\/p>\n

Fytokanabinoidy<\/strong>: Jedn\u00e1 se o kanabinoidy, kter\u00e9 jsou p\u0159irozen\u011b produkov\u00e1ny rostlinou konop\u00ed. Nejzn\u00e1m\u011bj\u0161\u00edmi a nejl\u00e9pe prozkouman\u00fdmi fytokanabinoidy jsou tetrahydrokanabinol (THC) a kanabidiol (CBD).<\/p>\n

THC je hlavn\u00ed psychoaktivn\u00ed slou\u010deninou konop\u00ed, kter\u00e1 je zodpov\u011bdn\u00e1 za \u201ehigh\u201c neboli euforick\u00fd \u00fa\u010dinek. M\u00e1 tak\u00e9 potenci\u00e1ln\u00ed terapeutick\u00e9 \u00fa\u010dinky, jako je \u00faleva od bolesti a stimulace chuti k j\u00eddlu. CBD je dal\u0161\u00ed d\u016fle\u017eit\u00fd kanabinoid, kter\u00fd se v konop\u00ed nach\u00e1z\u00ed. Na rozd\u00edl od THC nen\u00ed CBD psychoaktivn\u00ed a nezp\u016fsobuje \u201esjet\u00ed\u201c. Pozornost p\u0159itahuje d\u00edky sv\u00fdm potenci\u00e1ln\u00edm terapeutick\u00fdm \u00fa\u010dink\u016fm, v\u010detn\u011b protiz\u00e1n\u011btliv\u00fdch, analgetick\u00fdch a proti\u00fazkostn\u00fdch vlastnost\u00ed.<\/p>\n

\"Wie<\/p>\n

Endokanabinoidy:<\/strong> Jedn\u00e1 se o kanabinoidy, kter\u00e9 na\u0161e t\u011blo p\u0159irozen\u011b produkuje. Anandamid a 2-arachidonoylglycerol (2-AG) jsou dva hlavn\u00ed endokanabinoidy, kter\u00e9 byly identifikov\u00e1ny. Hraj\u00ed roli p\u0159i udr\u017eov\u00e1n\u00ed homeost\u00e1zy t\u00edm, \u017ee se v\u00e1\u017eou na kanabinoidn\u00ed receptory v endokanabinoidn\u00edm syst\u00e9mu.<\/p>\n

Syntetick\u00e9 kanabinoidy:<\/strong> Jedn\u00e1 se o kanabinoidy, kter\u00e9 jsou chemicky syntetizov\u00e1ny v laborato\u0159i. \u010casto maj\u00ed napodobit \u00fa\u010dinky p\u0159\u00edrodn\u00edch kanabinoid\u016f a n\u011bkdy se pou\u017e\u00edvaj\u00ed pro v\u00fdzkumn\u00e9 \u00fa\u010dely nebo dokonce neleg\u00e1ln\u011b jako rekrea\u010dn\u00ed drogy. Syntetick\u00e9 kanabinoidy mohou m\u00edt nep\u0159edv\u00eddateln\u00e9 a potenci\u00e1ln\u011b nebezpe\u010dn\u00e9 \u00fa\u010dinky na lidsk\u00e9 zdrav\u00ed.<\/p>\n

V\u00fdskyt kanabinoid\u016f<\/h3>\n

Dva hlavn\u00ed zdroje kanabinoid\u016f jsou:<\/p>\n

Rostlina konop\u00ed: Je nejzn\u00e1m\u011bj\u0161\u00edm zdrojem kanabinoid\u016f, kter\u00e9 jsou produkov\u00e1ny ve speci\u00e1ln\u00edch \u017el\u00e1z\u00e1ch zvan\u00fdch trichomy. Dva nejb\u011b\u017en\u011bj\u0161\u00ed a nejl\u00e9pe prozkouman\u00e9 kanabinoidy v rostlin\u011b konop\u00ed jsou delta-9-tetrahydrokanabinol (THC) a kanabidiol (CBD). Existuje v\u0161ak v\u00edce ne\u017e 100 dal\u0161\u00edch kanabinoid\u016f, z nich\u017e ka\u017ed\u00fd m\u00e1 jin\u00e9 \u00fa\u010dinky a potenci\u00e1ln\u00ed terapeutick\u00e9 vlastnosti.<\/p>\n

Konop\u00ed: Konop\u00ed je odr\u016fda rostliny konop\u00ed, kter\u00e1 se p\u011bstuje pro pr\u016fmyslov\u00e9 vyu\u017eit\u00ed, nap\u0159\u00edklad pro v\u00fdrobu vl\u00e1kna, semen a oleje. M\u00e1 n\u00edzk\u00fd obsah THC (obvykle m\u00e9n\u011b ne\u017e 0,3 %), co\u017e znamen\u00e1, \u017ee nevyvol\u00e1v\u00e1 psychoaktivn\u00ed \u00fa\u010dinky spojen\u00e9 s konop\u00edm. Konop\u00ed je tak\u00e9 v\u00fdznamn\u00fdm zdrojem CBD, kter\u00e9 se pou\u017e\u00edv\u00e1 v r\u016fzn\u00fdch zdravotn\u00edch a wellness produktech.<\/p>\n

Je t\u0159eba poznamenat, \u017ee kanabinoidy lze syntetizovat i v laborato\u0159i, ale hlavn\u00edmi p\u0159\u00edrodn\u00edmi zdroji kanabinoid\u016f jsou rostliny konop\u00ed a konop\u00ed. Obsah a druh kanabinoid\u016f v t\u011bchto rostlin\u00e1ch se m\u016f\u017ee zna\u010dn\u011b li\u0161it v z\u00e1vislosti na kmeni, podm\u00ednk\u00e1ch p\u011bstov\u00e1n\u00ed a metod\u00e1ch kultivace.<\/p>\n

\"Quellen<\/p>\n

Syntetick\u00e9 a p\u0159\u00edrodn\u00ed kanabinoidy<\/h3>\n

Kanabinoidy lze obecn\u011b rozd\u011blit do dvou skupin: p\u0159\u00edrodn\u00ed kanabinoidy a syntetick\u00e9 kanabinoidy.<\/p>\n

P\u0159\u00edrodn\u00ed kanabinoidy jsou slou\u010deniny, kter\u00e9 se p\u0159irozen\u011b vyskytuj\u00ed v rostlin\u011b konop\u00ed. Mezi nejzn\u00e1m\u011bj\u0161\u00ed a nejl\u00e9pe prozkouman\u00e9 p\u0159\u00edrodn\u00ed kanabinoidy pat\u0159\u00ed THC, CBD, kanabinol (CBN) a kanabigerol (CBG).<\/p>\n

Syntetick\u00e9 kanabinoidy jsou slou\u010deniny, kter\u00e9 se um\u011ble vyr\u00e1b\u011bj\u00ed v laborato\u0159i, aby napodobily \u00fa\u010dinky p\u0159\u00edrodn\u00edch kanabinoid\u016f. \u010casto jsou navr\u017eeny tak, aby interagovaly se stejn\u00fdmi receptory v endokanabinoidn\u00edm syst\u00e9mu jako p\u0159\u00edrodn\u00ed kanabinoidy. Syntetick\u00e9 kanabinoidy se n\u011bkdy ozna\u010duj\u00ed jako \u201edesignov\u00e9 drogy\u201c nebo \u201ev\u00fdzkumn\u00e9 chemik\u00e1lie\u201c. Obvykle jsou vyv\u00edjeny pro \u00fa\u010dely l\u00e9ka\u0159sk\u00e9ho v\u00fdzkumu, ale jsou tak\u00e9 zneu\u017e\u00edv\u00e1ny jako rekrea\u010dn\u00ed drogy.<\/p>\n

Hlavn\u00ed rozd\u00edl mezi syntetick\u00fdmi a p\u0159\u00edrodn\u00edmi kanabinoidy spo\u010d\u00edv\u00e1 v tom, \u017ee syntetick\u00e9 kanabinoidy se mohou v\u00fdrazn\u011b li\u0161it svou silou, \u00fa\u010dinky a bezpe\u010dnostn\u00edm profilem. D\u00edky t\u011bmto rozd\u00edl\u016fm jsou potenci\u00e1ln\u011b nebezpe\u010dn\u011bj\u0161\u00ed ne\u017e p\u0159\u00edrodn\u00ed kanabinoidy. Syntetick\u00e9 kanabinoidy jsou tak\u00e9 spojeny s \u0159adou vedlej\u0161\u00edch \u00fa\u010dink\u016f, v\u010detn\u011b siln\u00e9 \u00fazkosti, halucinac\u00ed, paranoie, bu\u0161en\u00ed srdce a dokonce i \u017eivot ohro\u017euj\u00edc\u00edch stav\u016f.<\/p>\n

Shrnuto, p\u0159\u00edrodn\u00ed kanabinoidy, jako je THC a CBD, jsou podrobn\u011b prozkoum\u00e1ny a maj\u00ed zn\u00e1m\u00e9 \u00fa\u010dinky a nejsou toxick\u00e9, zat\u00edmco syntetick\u00e9 kanabinoidy mohou b\u00fdt velmi odli\u0161n\u00e9 a nesou s sebou vy\u0161\u0161\u00ed riziko ne\u017e\u00e1douc\u00edch \u00fa\u010dink\u016f. Pou\u017e\u00edv\u00e1n\u00ed p\u0159\u00edrodn\u00edch kanabinoid\u016f k l\u00e9\u010debn\u00fdm \u00fa\u010del\u016fm je l\u00e9pe prozkoum\u00e1no a regulov\u00e1no ne\u017e pou\u017e\u00edv\u00e1n\u00ed syntetick\u00fdch kanabinoid\u016f, kter\u00e9 jsou \u010dasto pova\u017eov\u00e1ny za rizikov\u011bj\u0161\u00ed variantu vzhledem k jejich potenci\u00e1lu nep\u0159edv\u00eddateln\u00fdch a \u0161kodliv\u00fdch \u00fa\u010dink\u016f.<\/p>\n

\"Synthetische<\/p>\n

Jak kanabinoidy v l\u00e9\u010debn\u00e9m konop\u00ed funguj\u00ed?<\/h2>\n

Interakce mezi kanabinoidy a endokanabinoidn\u00edm syst\u00e9mem a souvisej\u00edc\u00ed potenci\u00e1ln\u00ed aplikace jsou p\u0159edm\u011btem velk\u00e9ho v\u00fdzkumn\u00e9ho z\u00e1jmu. L\u00e9\u010debn\u00e9 konop\u00ed, kde se konop\u00ed nebo kanabinoidy pou\u017e\u00edvaj\u00ed k l\u00e9\u010debn\u00fdm \u00fa\u010del\u016fm, si z\u00edskalo pozornost u r\u016fzn\u00fdch onemocn\u011bn\u00ed, jako je chronick\u00e1 bolest, epilepsie, roztrou\u0161en\u00e1 skler\u00f3za a dal\u0161\u00ed.<\/p>\n

THC (Delta-9-Tetrahydrocannabinol)<\/h3>\n

THC je nejd\u016fle\u017eit\u011bj\u0161\u00ed psychoaktivn\u00ed slo\u017ekou konop\u00ed. V\u00e1\u017ee se na kanabinoidn\u00ed receptory v mozku a centr\u00e1ln\u00edm nervov\u00e9m syst\u00e9mu. Tato interakce vede k uvol\u0148ov\u00e1n\u00ed dopaminu a dal\u0161\u00edch neurotransmiter\u016f, co\u017e tak\u00e9 vede k \u201eopojen\u00ed\u201c spojen\u00e9mu s u\u017e\u00edv\u00e1n\u00edm konop\u00ed. THC m\u00e1 tak\u00e9 analgetick\u00e9 (bolest ti\u0161\u00edc\u00ed) vlastnosti.<\/p>\n

\"THC<\/p>\n

CBD (Kanabidiol)<\/h3>\n

CBD je dal\u0161\u00ed d\u016fle\u017eit\u00fd kanabinoid obsa\u017een\u00fd v konop\u00ed, kter\u00fd v\u0161ak nem\u00e1 stejn\u00e9 psychoaktivn\u00ed \u00fa\u010dinky jako THC. Uv\u00e1d\u00ed se, \u017ee m\u00e1 protiz\u00e1n\u011btliv\u00e9, analgetick\u00e9, anxiolytick\u00e9 (proti \u00fazkosti) a antipsychotick\u00e9 vlastnosti. \u00da\u010dinky CBD jsou slo\u017eit\u00e9 a ne zcela objasn\u011bn\u00e9, ale zd\u00e1 se, \u017ee moduluje \u00fa\u010dinky THC a ovliv\u0148uje r\u016fzn\u00e9 sign\u00e1ln\u00ed dr\u00e1hy v t\u011ble.<\/p>\n

Dal\u0161\u00ed kanabinoidy<\/h3>\n

V konop\u00ed je v\u00edce ne\u017e 100 r\u016fzn\u00fdch kanabinoid\u016f, z nich\u017e ka\u017ed\u00fd m\u00e1 sv\u00e9 vlastn\u00ed potenci\u00e1ln\u00ed \u00fa\u010dinky. Nap\u0159\u00edklad kanabinol (CBN) m\u00e1 \u00fadajn\u011b uklid\u0148uj\u00edc\u00ed \u00fa\u010dinek, zat\u00edmco kanabigerol (CBG) m\u016f\u017ee m\u00edt protiz\u00e1n\u011btliv\u00fd \u00fa\u010dinek.<\/p>\n

Co je to endokanabinoidn\u00ed syst\u00e9m?<\/h2>\n

Endokanabinoidn\u00ed syst\u00e9m (ECS) je komplexn\u00ed bun\u011b\u010dn\u00fd signaliza\u010dn\u00ed syst\u00e9m v t\u011ble, kter\u00fd hraje kl\u00ed\u010dovou roli v regulaci \u0159ady d\u016fle\u017eit\u00fdch fyziologick\u00fdch proces\u016f.<\/p>\n

ECS se skl\u00e1d\u00e1 ze t\u0159\u00ed hlavn\u00edch slo\u017eek:<\/p>\n

    \n
  • Endokanabinoidy: Jedn\u00e1 se o p\u0159irozen\u011b se vyskytuj\u00edc\u00ed slou\u010deniny produkovan\u00e9 t\u011blem. Endokanabinoidy jsou syntetizov\u00e1ny na po\u017e\u00e1d\u00e1n\u00ed a p\u016fsob\u00ed jako sign\u00e1ln\u00ed molekuly t\u00edm, \u017ee se v\u00e1\u017eou na kanabinoidn\u00ed receptory.<\/li>\n
  • Kanabinoidn\u00ed receptory: Existuj\u00ed dva hlavn\u00ed typy kanabinoidn\u00edch receptor\u016f - CB1 a CB2. Receptory CB1 se nach\u00e1zej\u00ed p\u0159edev\u0161\u00edm v mozku a centr\u00e1ln\u00edm nervov\u00e9m syst\u00e9mu, zat\u00edmco receptory CB2 se \u010dast\u011bji vyskytuj\u00ed v imunitn\u00edch bu\u0148k\u00e1ch. Tyto receptory jsou b\u00edlkoviny, kter\u00e9 se nach\u00e1zej\u00ed na povrchu bun\u011bk a jsou zodpov\u011bdn\u00e9 za p\u0159\u00edjem a p\u0159enos sign\u00e1l\u016f z endokanabinoid\u016f.<\/li>\n
  • Enzymy: Enzymy jsou zodpov\u011bdn\u00e9 za synt\u00e9zu a degradaci endokanabinoid\u016f. Dva nejd\u016fle\u017eit\u011bj\u0161\u00ed enzymy jsou amidhydrol\u00e1za mastn\u00fdch kyselin (FAAH), kter\u00e1 rozkl\u00e1d\u00e1 anandamid, a monoacylglycerollip\u00e1za (MAGL), kter\u00e1 rozkl\u00e1d\u00e1 2-AG.<\/li>\n<\/ul>\n

    \"Was<\/p>\n

    Endokanabinoidn\u00ed syst\u00e9m se pod\u00edl\u00ed na regulaci cel\u00e9 \u0159ady fyziologick\u00fdch proces\u016f, mimo jin\u00e9:<\/p>\n

      \n
    • ECS hraje roli v modulaci vn\u00edm\u00e1n\u00ed a citlivosti bolesti.<\/li>\n
    • N\u00e1lada a emoce: Hraje roli v regulaci n\u00e1lady, \u00fazkosti a reakc\u00ed na stres.<\/li>\n
    • Chu\u0165 k j\u00eddlu a metabolismus - ECS ovliv\u0148uje chu\u0165 k j\u00eddlu a metabolismus a jeho dysregulace je spojena s obezitou.<\/li>\n
    • Reakce imunitn\u00edho syst\u00e9mu - ECS ovliv\u0148uje aktivitu imunitn\u00edch bun\u011bk a z\u00e1n\u011bt.<\/li>\n
    • Sp\u00e1nek - ovliv\u0148uje sp\u00e1nkov\u00e9 vzorce a cyklus sp\u00e1nku a bd\u011bn\u00ed.<\/li>\n
    • Neuroprotekce - P\u0159edpokl\u00e1d\u00e1 se, \u017ee ECS hraje neuroprotektivn\u00ed roli a m\u016f\u017ee ovliv\u0148ovat nemoci, jako je epilepsie a neurodegenerativn\u00ed onemocn\u011bn\u00ed.<\/li>\n<\/ul>\n

      Prob\u00edhaj\u00edc\u00ed v\u00fdzkum endokanabinoidn\u00edho syst\u00e9mu vedl k v\u00fdvoji l\u00e9k\u016f a terapi\u00ed zam\u011b\u0159en\u00fdch na ECS u r\u016fzn\u00fdch onemocn\u011bn\u00ed. Krom\u011b toho je interakce mezi ECS a kanabinoidy obsa\u017een\u00fdmi v rostlin\u011b konop\u00ed (nap\u0159. THC a CBD) obzvl\u00e1\u0161t\u011b zaj\u00edmav\u00e1 vzhledem k jejich potenci\u00e1ln\u00edm terapeutick\u00fdm \u00fa\u010dink\u016fm, a\u010dkoli k \u00fapln\u00e9mu pochopen\u00ed t\u011bchto interakc\u00ed je zapot\u0159eb\u00ed dal\u0161\u00edho v\u00fdzkumu.<\/p>\n

      \u00da\u010dinek kanabinoid\u016f na t\u011blo a mysl<\/h2>\n

      \u00da\u010dinky kanabinoid\u016f na t\u011blo a mysl se mohou li\u0161it v z\u00e1vislosti na kmeni, jeho koncentraci a individu\u00e1ln\u00edch rozd\u00edlech v metabolismu a citlivosti. Zde je p\u0159ehled \u00fa\u010dink\u016f kanabinoid\u016f.<\/p>\n

      Tetrahydrokanabinol\u00a0(THC)<\/h3>\n

      THC je hlavn\u00ed psychoaktivn\u00ed slou\u010denina v konop\u00ed, kter\u00e1 je zodpov\u011bdn\u00e1 za \u201ehigh\u201c nebo euforick\u00fd pocit \u010dasto spojovan\u00fd s u\u017e\u00edv\u00e1n\u00edm marihuany. Jej\u00ed \u00fa\u010dinky na t\u011blo a mysl zahrnuj\u00ed\u00b9:<\/p>\n

        \n
      • Euforie a uvoln\u011bn\u00ed: THC m\u016f\u017ee vyvolat pocit euforie, uvoln\u011bn\u00ed a zm\u011bn\u011bn\u00e9ho vn\u00edm\u00e1n\u00ed \u010dasu.<\/li>\n
      • Zm\u011bn\u011bn\u00e9 vn\u00edm\u00e1n\u00ed: THC m\u016f\u017ee zkreslit smyslov\u00e9 vn\u00edm\u00e1n\u00ed a zp\u016fsobit, \u017ee jedinci vn\u00edmaj\u00ed sv\u00e9 okol\u00ed jinak.<\/li>\n
      • Zv\u00fd\u0161en\u00e1 chu\u0165 k j\u00eddlu: THC m\u016f\u017ee stimulovat chu\u0165 k j\u00eddlu a v\u00e9st k p\u0159ej\u00edd\u00e1n\u00ed.<\/li>\n
      • Zhor\u0161en\u00e1 pam\u011b\u0165 a koordinace: THC m\u016f\u017ee zhor\u0161it kr\u00e1tkodobou pam\u011b\u0165, pozornost a motorickou koordinaci.<\/li>\n
      • \u00dazkost a paranoia: Vy\u0161\u0161\u00ed d\u00e1vky THC mohou u n\u011bkter\u00fdch lid\u00ed vyvolat \u00fazkost a paranoiu.<\/li>\n
      • \u00daleva od bolesti: THC m\u00e1 vlastnosti tlum\u00edc\u00ed bolest a n\u011bkdy se pou\u017e\u00edv\u00e1 k l\u00e9ka\u0159sk\u00e9 l\u00e9\u010db\u011b bolesti.<\/li>\n<\/ul>\n

        Kanabidiol (CBD)<\/h3>\n

        CBD je nepsychoaktivn\u00ed kanabinoid zn\u00e1m\u00fd sv\u00fdmi potenci\u00e1ln\u00edmi l\u00e9\u010debn\u00fdmi \u00fa\u010dinky. Nevyvol\u00e1v\u00e1 \u201ehigh\u201c jako THC a m\u016f\u017ee dokonce p\u016fsobit proti n\u011bkter\u00fdm psychoaktivn\u00edm \u00fa\u010dink\u016fm THC. Mezi \u00fa\u010dinky CBD pat\u0159\u00ed\u00b2:<\/p>\n

          \n
        • Sn\u00ed\u017een\u00ed \u00fazkosti: CBD bylo zkoum\u00e1no pro sv\u016fj potenci\u00e1l sni\u017eovat \u00fazkost a podporovat relaxaci.<\/li>\n
        • Antipsychotick\u00e9 \u00fa\u010dinky: CBD m\u016f\u017ee m\u00edt antipsychotick\u00e9 \u00fa\u010dinky a m\u016f\u017ee b\u00fdt u\u017eite\u010dn\u00e9 p\u0159i stavech, jako je schizofrenie.<\/li>\n
        • Tlumen\u00ed bolesti: CBD se uk\u00e1zalo jako slibn\u00e9 p\u0159i tlumen\u00ed bolesti a z\u00e1n\u011btu.<\/li>\n
        • Sn\u00ed\u017een\u00ed po\u010dtu z\u00e1chvat\u016f: Epidiolex, l\u00e9k na b\u00e1zi CBD, je schv\u00e1len pro l\u00e9\u010dbu n\u011bkter\u00fdch typ\u016f z\u00e1chvat\u016f.<\/li>\n
        • Neuroprotektivn\u00ed \u00fa\u010dinky: Antioxida\u010dn\u00ed a protiz\u00e1n\u011btliv\u00e9 vlastnosti CBD nazna\u010duj\u00ed potenci\u00e1l chr\u00e1nit nervov\u00fd syst\u00e9m.<\/li>\n<\/ul>\n

          L\u00e9ka\u0159sk\u00e9 vyu\u017eit\u00ed kanabinoid\u016f<\/h2>\n

          L\u00e9\u010dba bolesti<\/h3>\n

          Kanabinoidy, zejm\u00e9na THC a CBD, prok\u00e1zaly potenci\u00e1l p\u0159i l\u00e9\u010db\u011b r\u016fzn\u00fdch typ\u016f bolesti, v\u010detn\u011b chronick\u00e9 bolesti, neuropatick\u00e9 bolesti a bolesti spojen\u00e9 s onemocn\u011bn\u00edmi, jako je roztrou\u0161en\u00e1 skler\u00f3za. Studie nazna\u010duj\u00ed, \u017ee kanabinoidy mohou modulovat vn\u00edm\u00e1n\u00ed bolesti prost\u0159ednictv\u00edm interakce s kanabinoidn\u00edmi receptory v nervov\u00e9m syst\u00e9mu.\u2074.<\/p>\n

          \"Die<\/p>\n

          Neurologick\u00e9 poruchy<\/h3>\n

          Kanabinoidy byly zkoum\u00e1ny pro sv\u016fj potenci\u00e1l v l\u00e9\u010db\u011b neurologick\u00fdch poruch, jako je epilepsie, roztrou\u0161en\u00e1 skler\u00f3za a Parkinsonova choroba.\u2075 Pozornost p\u0159itahuje zejm\u00e9na CBD d\u00edky sv\u00fdm antikonvulzivn\u00edm vlastnostem a potenci\u00e1ln\u00edm neuroprotektivn\u00edm \u00fa\u010dink\u016fm.\u2076.<\/p>\n

          P\u0159\u00edznaky souvisej\u00edc\u00ed s rakovinou<\/h3>\n

          Kanabinoidy byly zkoum\u00e1ny pro sv\u016fj potenci\u00e1l zm\u00edrnit p\u0159\u00edznaky souvisej\u00edc\u00ed s rakovinou, jako je nevolnost a zvracen\u00ed vyvolan\u00e9 chemoterapi\u00ed\u2077 a tak\u00e9 bolest a ztr\u00e1ta chuti k j\u00eddlu.\u2078 Syntetick\u00e9 kanabinoidy, jako je dronabinol a nabilon, jsou v n\u011bkter\u00fdch zem\u00edch k l\u00e9\u010db\u011b t\u011bchto p\u0159\u00edznak\u016f povoleny.<\/p>\n

          Mo\u017en\u00e1 rizika a vedlej\u0161\u00ed \u00fa\u010dinky kanabinoid\u016f<\/h2>\n

          Individu\u00e1ln\u00ed reakce na kanabinoidy se mohou zna\u010dn\u011b li\u0161it a k \u00fapln\u00e9mu pochopen\u00ed jejich \u00fa\u010dink\u016f je zapot\u0159eb\u00ed dal\u0161\u00edho v\u00fdzkumu. Zde jsou uvedena n\u011bkter\u00e1 mo\u017en\u00e1 rizika a ne\u017e\u00e1douc\u00ed \u00fa\u010dinky kanabinoid\u016f:<\/p>\n

          Psychologick\u00e9 \u00fa\u010dinky: THC, psychoaktivn\u00ed l\u00e1tka obsa\u017een\u00e1 v konop\u00ed, m\u016f\u017ee zp\u016fsobovat r\u016fzn\u00e9 psychick\u00e9 \u00fa\u010dinky, jako je \u00fazkost, paranoia, halucinace a zhor\u0161en\u00ed kognitivn\u00edch funkc\u00ed. Tyto \u00fa\u010dinky jsou v\u00fdrazn\u011bj\u0161\u00ed u lid\u00ed, kte\u0159\u00ed jsou na THC citliv\u00ed nebo jej konzumuj\u00ed ve vysok\u00fdch d\u00e1vk\u00e1ch.<\/p>\n

          Z\u00e1vislost a n\u00e1vyk: Pravideln\u00e9 u\u017e\u00edv\u00e1n\u00ed produkt\u016f obsahuj\u00edc\u00edch THC m\u016f\u017ee u n\u011bkter\u00fdch lid\u00ed v\u00e9st ke vzniku z\u00e1vislosti a n\u00e1vyku. To m\u016f\u017ee v\u00e9st k abstinen\u010dn\u00edm p\u0159\u00edznak\u016fm, jako je podr\u00e1\u017ed\u011bnost, nespavost, sn\u00ed\u017een\u00e1 chu\u0165 k j\u00eddlu a v\u00fdkyvy n\u00e1lad, kdy\u017e se l\u00e1tka nekonzumuje.<\/p>\n

          Zhor\u0161en\u00ed motorick\u00fdch funkc\u00ed: THC m\u016f\u017ee zhor\u0161it motorickou koordinaci a reak\u010dn\u00ed dobu, co\u017e m\u016f\u017ee zv\u00fd\u0161it riziko nehod, zejm\u00e9na p\u0159i \u0159\u00edzen\u00ed nebo obsluze t\u011b\u017ek\u00fdch stroj\u016f.<\/p>\n

          Kardiovaskul\u00e1rn\u00ed \u00fa\u010dinky: U\u017e\u00edv\u00e1n\u00ed konop\u00ed m\u016f\u017ee v\u00e9st ke zv\u00fd\u0161en\u00ed srde\u010dn\u00ed frekvence, co\u017e m\u016f\u017ee p\u0159edstavovat riziko pro osoby s ji\u017e existuj\u00edc\u00edm srde\u010dn\u00edm onemocn\u011bn\u00edm, a tedy zv\u00fd\u0161it riziko kardiovaskul\u00e1rn\u00edch p\u0159\u00edhod u vn\u00edmav\u00fdch osob.<\/p>\n

          Probl\u00e9my s d\u00fdchac\u00edm syst\u00e9mem: Kou\u0159en\u00ed konop\u00ed m\u016f\u017ee dr\u00e1\u017edit pl\u00edce a v\u00e9st k d\u00fdchac\u00edm pot\u00ed\u017e\u00edm, podobn\u011b jako rizika spojen\u00e1 s kou\u0159en\u00edm tab\u00e1ku. Dlouhodob\u00e9 u\u017e\u00edv\u00e1n\u00ed m\u016f\u017ee p\u0159isp\u011bt ke vzniku chronick\u00e9 bronchitidy a dal\u0161\u00edch probl\u00e9m\u016f souvisej\u00edc\u00edch s pl\u00edcemi.<\/p>\n

          \"\"<\/p>\n

          Kognitivn\u00ed porucha: Chronick\u00e9 u\u017e\u00edv\u00e1n\u00ed konop\u00ed s vysok\u00fdm obsahem THC m\u016f\u017ee v\u00e9st k poruch\u00e1m kognitivn\u00edch funkc\u00ed, zejm\u00e9na pam\u011bti, pozornosti a schopnosti u\u010den\u00ed. To je obzvl\u00e1\u0161t\u011b kritick\u00e9 u osob mlad\u0161\u00edch 25 let, jejich\u017e mozek se st\u00e1le vyv\u00edj\u00ed.<\/p>\n

          Du\u0161evn\u00ed zdrav\u00ed: N\u011bkte\u0159\u00ed lid\u00e9 u\u017e\u00edvaj\u00ed konop\u00ed ke zm\u00edrn\u011bn\u00ed p\u0159\u00edznak\u016f \u00fazkosti a deprese. Intenzivn\u00ed nebo dlouhodob\u00e9 u\u017e\u00edv\u00e1n\u00ed, zejm\u00e9na kmen\u016f s vysok\u00fdm obsahem THC, v\u0161ak m\u016f\u017ee zv\u00fd\u0161it riziko vzniku nebo zhor\u0161en\u00ed du\u0161evn\u00edch poruch, zejm\u00e9na u osob s predispozic\u00ed k nim.<\/p>\n

          Interakce s l\u00e9ky: Kanabinoidy mohou interagovat s n\u011bkter\u00fdmi l\u00e9ky a naru\u0161ovat jejich \u00fa\u010dinnost nebo zp\u016fsobovat ne\u017e\u00e1douc\u00ed \u00fa\u010dinky. P\u0159ed u\u017e\u00edv\u00e1n\u00edm kanabinoid\u016f je d\u016fle\u017eit\u00e9 poradit se s l\u00e9ka\u0159em, zejm\u00e9na pokud u\u017e\u00edv\u00e1te jin\u00e9 l\u00e9ky.<\/p>\n

          Je d\u016fle\u017eit\u00e9, abyste se o u\u017e\u00edv\u00e1n\u00ed kanabinoid\u016f rozhodovali informovan\u011b. Pokud zva\u017eujete u\u017e\u00edv\u00e1n\u00ed kanabinoid\u016f k l\u00e9\u010debn\u00fdm \u00fa\u010del\u016fm, je vhodn\u00e9 poradit se se zdravotn\u00edkem, kter\u00fd v\u00e1m porad\u00ed v z\u00e1vislosti na va\u0161em individu\u00e1ln\u00edm zdravotn\u00edm stavu a pot\u0159eb\u00e1ch.<\/p>\n

          Jak pou\u017e\u00edvat kanabinoidy?<\/h2>\n

          U\u017e\u00edv\u00e1n\u00ed kanabinoid\u016f, zejm\u00e9na THC a CBD, si z\u00edskalo oblibu d\u00edky jejich potenci\u00e1ln\u00edm l\u00e9\u010debn\u00fdm \u00fa\u010dink\u016fm. Zde se dozv\u00edte, jak je m\u016f\u017eete pou\u017e\u00edvat:<\/p>\n

          Kou\u0159en\u00ed<\/strong><\/p>\n

          Jedn\u00e1 se o jednu z nejb\u011b\u017en\u011bj\u0161\u00edch metod u\u017e\u00edv\u00e1n\u00ed kanabinoid\u016f, zejm\u00e9na THC. Kanabinoidy se rychle vst\u0159eb\u00e1vaj\u00ed do krevn\u00edho ob\u011bhu prost\u0159ednictv\u00edm plic. Kou\u0159en\u00ed v\u0161ak m\u016f\u017ee m\u00edt negativn\u00ed \u00fa\u010dinky na zdrav\u00ed plic a nedoporu\u010duje se pro dlouhodob\u00e9 u\u017e\u00edv\u00e1n\u00ed.<\/p>\n

          Peror\u00e1ln\u00ed po\u017eit\u00ed<\/strong><\/p>\n

          Dal\u0161\u00ed mo\u017enost\u00ed jsou jedl\u00e9 produkty napu\u0161t\u011bn\u00e9 kanabinoidy. Pat\u0159\u00ed mezi n\u011b kol\u00e1\u010dky, gumov\u00ed medv\u00eddci, \u010dokol\u00e1dy a dal\u0161\u00ed. Kanabinoidy se vst\u0159eb\u00e1vaj\u00ed tr\u00e1vic\u00edm syst\u00e9mem, tak\u017ee \u00fa\u010dinky mohou trvat d\u00e9le (\u010dasto 30 minut a\u017e 2 hodiny) a b\u00fdvaj\u00ed dlouhodob\u011bj\u0161\u00ed.<\/p>\n

          \"Wie<\/p>\n

          Sublingv\u00e1ln\u00ed<\/strong><\/p>\n

          Pat\u0159\u00ed sem tinktury, oleje a spreje, kter\u00e9 se aplikuj\u00ed pod jazyk. Tato metoda umo\u017e\u0148uje rychlej\u0161\u00ed vst\u0159eb\u00e1v\u00e1n\u00ed kanabinoid\u016f do krevn\u00edho ob\u011bhu prost\u0159ednictv\u00edm c\u00e9v pod jazykem. \u00da\u010dinek se obvykle dostav\u00ed do 10-20 minut.<\/p>\n

          Inhalace<\/strong><\/p>\n

          Krom\u011b kou\u0159en\u00ed je dal\u0161\u00ed inhala\u010dn\u00ed metodou vaporizace. Vaporiz\u00e9ry zah\u0159\u00edvaj\u00ed kanabinoidy na teplotu, p\u0159i kter\u00e9 se uvol\u0148uj\u00ed jako p\u00e1ra, ale neho\u0159\u00ed. T\u00edm se sni\u017euje potenci\u00e1ln\u00ed po\u0161kozen\u00ed plic spojen\u00e9 s kou\u0159en\u00edm.<\/p>\n

          Nosn\u00ed spreje<\/strong><\/p>\n

          Nosn\u00ed spreje jsou ur\u010deny k dod\u00e1v\u00e1n\u00ed kanabinoid\u016f nosn\u00ed sliznic\u00ed, co\u017e umo\u017e\u0148uje jejich rychlou absorpci do krevn\u00edho ob\u011bhu.<\/p>\n

          N\u00e1plasti<\/strong><\/p>\n

          Transderm\u00e1ln\u00ed n\u00e1plasti obohacen\u00e9 kanabinoidy lze nalepit na k\u016f\u017ei. V pr\u016fb\u011bhu \u010dasu pomalu uvol\u0148uj\u00ed kanabinoidy do krevn\u00edho ob\u011bhu.<\/p>\n

          Lok\u00e1ln\u00ed aplikace<\/strong><\/p>\n

          Kr\u00e9my, ple\u0165ov\u00e9 vody, balz\u00e1my a oleje obohacen\u00e9 kanabinoidy lze aplikovat p\u0159\u00edmo na k\u016f\u017ei. \u010casto se pou\u017e\u00edvaj\u00ed k lok\u00e1ln\u00ed \u00falev\u011b od bolesti nebo z\u00e1n\u011btu.<\/p>\n

          \"Dosierungshinweise<\/p>\n

          Pokyny pro d\u00e1vkov\u00e1n\u00ed a bezpe\u010dnostn\u00ed pokyny<\/h2>\n

          P\u0159i d\u00e1vkov\u00e1n\u00ed kanabinoid\u016f je t\u0159eba zv\u00e1\u017eit n\u011bkolik d\u016fle\u017eit\u00fdch faktor\u016f. Kanabinoidy jsou \u00fa\u010dinn\u00e9 l\u00e1tky obsa\u017een\u00e9 v konop\u00ed, kter\u00e9 v t\u011ble interaguj\u00ed s endokanabinoidn\u00edm syst\u00e9mem, jen\u017e se pod\u00edl\u00ed na regulaci r\u016fzn\u00fdch fyziologick\u00fdch proces\u016f.<\/p>\n

          D\u00e1vkov\u00e1n\u00ed se m\u016f\u017ee zna\u010dn\u011b li\u0161it a z\u00e1vis\u00ed na faktorech, jako je konkr\u00e9tn\u00ed kanabinoid, individu\u00e1ln\u00ed tolerance, po\u017eadovan\u00fd \u00fa\u010dinek a zp\u016fsob konzumace. Zde jsou n\u011bkter\u00e9 \u00favahy, kter\u00e9 je t\u0159eba m\u00edt na pam\u011bti:<\/p>\n

            \n
          1. Typ kanabinoidu<\/strong> - Dva nejzn\u00e1m\u011bj\u0161\u00ed kanabinoidy jsou THC (tetrahydrokanabinol) a CBD (kanabidiol). THC je zodpov\u011bdn\u00fd za psychoaktivn\u00ed \u00fa\u010dinky konop\u00ed, zat\u00edmco CBD nen\u00ed psychoaktivn\u00ed a m\u00e1 potenci\u00e1ln\u00ed terapeutick\u00e9 \u00fa\u010dinky. R\u016fzn\u00e9 kanabinoidy mohou m\u00edt r\u016fzn\u00e9 \u00fa\u010dinky a vy\u017eaduj\u00ed r\u016fzn\u00e9 d\u00e1vkov\u00e1n\u00ed.<\/li>\n
          2. Tolerance<\/strong> - Individu\u00e1ln\u00ed tolerance ke kanabinoid\u016fm se m\u016f\u017ee zna\u010dn\u011b li\u0161it. Za\u010d\u00e1te\u010dn\u00edci a lid\u00e9 s n\u00edzkou toleranc\u00ed by m\u011bli za\u010d\u00edt s ni\u017e\u0161\u00edmi d\u00e1vkami, aby se vyhnuli ne\u017e\u00e1douc\u00edm \u00fa\u010dink\u016fm.<\/li>\n<\/ol>\n

            3. T\u011blesn\u00e1 hmotnost a metabolismus<\/strong> - t\u011blesn\u00e1 hmotnost a metabolismus mohou ovlivnit zpracov\u00e1n\u00ed kanabinoid\u016f v t\u011ble. Obecn\u011b plat\u00ed, \u017ee lid\u00e9 s vy\u0161\u0161\u00ed t\u011blesnou hmotnost\u00ed mohou vy\u017eadovat o n\u011bco vy\u0161\u0161\u00ed d\u00e1vky.<\/p>\n

            4. Za\u010dn\u011bte s n\u00edzkou d\u00e1vkou a postupujte pomalu<\/strong> - toto je b\u011b\u017en\u00e9 vod\u00edtko pro za\u010d\u00e1te\u010dn\u00edky. Za\u010dn\u011bte s n\u00edzkou d\u00e1vkou a postupn\u011b ji zvy\u0161ujte, dokud nedos\u00e1hnete po\u017eadovan\u00e9ho \u00fa\u010dinku. T\u00edm se vyhnete nadm\u011brn\u00e9 konzumaci a ne\u017e\u00e1douc\u00edm vedlej\u0161\u00edm \u00fa\u010dink\u016fm.<\/p>\n

            5. Sledujte \u00fa\u010dinky<\/strong> - v\u011bnujte pozornost tomu, jak va\u0161e t\u011blo reaguje na r\u016fzn\u00e9 d\u00e1vky. Sledujte \u00fa\u010dinky a podle pot\u0159eby upravte d\u00e1vkov\u00e1n\u00ed.<\/p>\n

            6. Mo\u017en\u00e9 interakce<\/strong> - Kanabinoidy mohou interagovat s n\u011bkter\u00fdmi l\u00e9ky. Pokud u\u017e\u00edv\u00e1te jin\u00e9 l\u00e9ky, pora\u010fte se p\u0159ed u\u017e\u00edv\u00e1n\u00edm kanabinoid\u016f s l\u00e9ka\u0159em.<\/p>\n

            7. Individu\u00e1ln\u00ed citlivost<\/strong> - N\u011bkte\u0159\u00ed lid\u00e9 mohou b\u00fdt na kanabinoidy citliv\u011bj\u0161\u00ed a dos\u00e1hnout \u00fa\u010dinku p\u0159i ni\u017e\u0161\u00edch d\u00e1vk\u00e1ch ne\u017e jin\u00ed.<\/p>\n

            \"Wie<\/p>\n

            8. Doba trv\u00e1n\u00ed \u00fa\u010dinku<\/strong> - Doba trv\u00e1n\u00ed \u00fa\u010dinku se m\u016f\u017ee li\u0161it v z\u00e1vislosti na zp\u016fsobu u\u017e\u00edv\u00e1n\u00ed. Kou\u0159en\u00ed nebo vapov\u00e1n\u00ed m\u016f\u017ee vyvolat rychlej\u0161\u00ed \u00fa\u010dinek, kter\u00fd rychleji odezn\u00ed, ne\u017e u edibles, u kter\u00fdch trv\u00e1 d\u00e9le, ne\u017e se dostav\u00ed, ale trvaj\u00ed d\u00e9le.<\/p>\n

            9. Osobn\u00ed zdravotn\u00ed stav<\/strong> - N\u011bkter\u00e9 zdravotn\u00ed stavy mohou ovlivnit, jak va\u0161e t\u011blo reaguje na kanabinoidy. Nap\u0159\u00edklad jedinci s \u00fazkostn\u00fdmi poruchami mus\u00ed b\u00fdt s THC opatrn\u00ed, proto\u017ee v n\u011bkter\u00fdch p\u0159\u00edpadech m\u016f\u017ee \u00fazkost zhor\u0161ovat.<\/p>\n

            Je d\u016fle\u017eit\u00e9 si uv\u011bdomit, \u017ee neexistuje univerz\u00e1ln\u00ed p\u0159\u00edstup k d\u00e1vkov\u00e1n\u00ed kanabinoid\u016f a to, co je dobr\u00e9 pro jednoho \u010dlov\u011bka, nemus\u00ed b\u00fdt nutn\u011b vhodn\u00e9 pro jin\u00e9ho. Pokud u\u017e\u00edv\u00e1te kanabinoidy poprv\u00e9, pora\u010fte se se sv\u00fdm l\u00e9ka\u0159em, abyste zajistili rozumn\u00e9 a bezpe\u010dn\u00e9 d\u00e1vkov\u00e1n\u00ed l\u00e9\u010debn\u00e9ho konop\u00ed.<\/p>\n

            Jak se mohu st\u00e1t pacientem s l\u00e9\u010debn\u00fdm konop\u00edm?<\/h2>\n

            Pokud trp\u00edte chronick\u00fdm onemocn\u011bn\u00edm, m\u016f\u017eete m\u00edt n\u00e1rok na l\u00e9\u010dbu l\u00e9\u010debn\u00fdm konop\u00edm. Pou\u017eit\u00ed l\u00e9\u010dby konop\u00edm nen\u00ed omezeno na konkr\u00e9tn\u00ed stavy nebo z\u00e1va\u017enost onemocn\u011bn\u00ed, ale lze ji pou\u017e\u00edt, pokud standardn\u00ed terapie nep\u0159inesla po\u017eadovan\u00e9 v\u00fdsledky.<\/p>\n

            Pokud se chcete dozv\u011bd\u011bt v\u00edce o tom, \u201ejak se st\u00e1t pacientem s konop\u00edm\u201c, p\u0159e\u010dt\u011bte si nyn\u00ed n\u00e1\u0161 \u010dl\u00e1nek.<\/p>\n

            Zdroje:<\/h3>\n
              \n
            1. Huestis, M.A. (2007). Pharmacokinetics of cannabinoids in humans. Chemistry & Biodiversity, 4(8), 1770-1804.<\/li>\n
            2. Campos, AC, Foga\u00e7a, MV, Sonego, AB, & Guimar\u00e3es, FS (2016). Cannabidiol, neuroprotection and neuropsychiatric disorders. Pharmacological Research, 112, 119-127.<\/li>\n
            3. Russo, E. B. (2008). Cannabinoids in the treatment of difficult-to-treat pain. Therapeutics and Clinical Risk Management, 4(1), 245-259.<\/li>\n
            4. Lynch, M.E., & Campbell, F. (2011). Cannabinoids for the treatment of chronic non-cancer pain; a systematic review of randomized trials. British Journal of Clinical Pharmacology, 72(5), 735-744.<\/li>\n
            5. Devinsky, O., Cross, J. H., Laux, L., Marsh, E., Miller, I., Nabbout, R., ... & Wright, S. (2017). Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome. New England Journal of Medicine, 376(21), 2011-2020.<\/li>\n
            6. Zuardi, A. W., Crippa, J. A. S., Hallak, J. E. C., & Pinto, J. P. (2010). Neuroimaging bei sozialer Angstst\u00f6rung: A Systematic Review of the Literature. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 34(4), 565-580.<\/li>\n
            7. Ahmedzai, S., Carlyle, D. L., Calder, I. T., & Moran, F. (2013). Anti-emetische Wirksamkeit und Toxizit\u00e4t von Nabilon, einem synthetischen Cannabinoid, bei der Chemotherapie von Lungenkrebs. British Journal of Cancer, 48(5), 657-663.<\/li>\n
            8. Whiting, PF, Wolff, RF, Deshpande, S., Di Nisio, M., Duffy, S., Hernandez, AV, ... & Kleijnen, J. (2015). Cannabinoids for medical use: A systematic review and meta-analysis. JAMA, 313(24), 2456-2473.<\/li>\n<\/ol>","protected":false},"excerpt":{"rendered":"

              Die in der Cannabispflanze nat\u00fcrlich vorkommenden Cannabinoide sind die Verbindungen, die mit Ihrem K\u00f6rper interagieren, um eine Reihe verschiedener potenzieller Vorteile und Wirkungen zu erzeugen. In diesem Artikel finden Sie alle relevanten Informationen, die Ihnen ein Verst\u00e4ndnis f\u00fcr die Bedeutung von Cannabinoiden im Bereich medizinisches Cannabis und deren Beitrag zur F\u00f6rderung Ihrer Gesundheit und Ihres Wohlbefindens vermitteln sollen.<\/p>","protected":false},"author":180,"featured_media":8250,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1898],"tags":[],"class_list":["post-7119","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lecebne-konopi"],"acf":[],"yoast_head":"\nCo jsou kanabinoidy? | mycannabis<\/title>\n<meta name=\"description\" content=\"Zjist\u011bte co jsou kanabinoidy | Objevte v\u00fdhody a roli kanabinoid\u016f v lidsk\u00e9m t\u011ble. 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